Date of Award
8-31-2018
Document Type
Campus Access Thesis
Degree Name
Master of Science (MS)
Department
Physics, Applied
First Advisor
Rahul V. Kulkarni
Second Advisor
D.V.G.L.N. Rao
Third Advisor
Chandra Yelleswarapu
Abstract
In this thesis, we study the steady-state behavior of a network of two interacting molecular species, non-coding small RNAs and messenger RNAs, to provide further insight into post-transcriptional regulation of stochastic gene expression. First, we demonstrate that the joint probability distribution of this network cannot be expressed a product of the marginal distributions for each species. Subsequently, we derive analytical expressions for the steady-state joint probability distribution for this network in the strong interaction limit.
Recommended Citation
Barr, Robert, "Stochastic Modeling of Post-Transcriptional Regulation of Gene Expression in the Limit of Strong Interactions" (2018). Graduate Masters Theses. 525.
https://scholarworks.umb.edu/masters_theses/525
Comments
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