Center for Personalized Cancer Therapy (CPCT) is improving tumor diagnostics in a way that will lead directly to more effective therapeutic regimens. The most significant outcome anticipated is for cancer patients and their families because the proposed approach will significantly help to flatten health disparities pertinent to cancer treatment. A The CPCT will work to develop affordable clinical tests that could be performed in community hospital settings. The CPCT informatics (highly sophisticated relational databases) also supports community physicians to most effectively choose optimized therapy, thus enabling the broadest possible population of patients to benefit from cutting-edge cancer research.