Date of Award
Campus Access Thesis
Master of Science (MS)
Rahul V. Kulkarni
In this thesis, we study the steady-state behavior of a network of two interacting molecular species, non-coding small RNAs and messenger RNAs, to provide further insight into post-transcriptional regulation of stochastic gene expression. First, we demonstrate that the joint probability distribution of this network cannot be expressed a product of the marginal distributions for each species. Subsequently, we derive analytical expressions for the steady-state joint probability distribution for this network in the strong interaction limit.
Barr, Robert, "Stochastic Modeling of Post-Transcriptional Regulation of Gene Expression in the Limit of Strong Interactions" (2018). Graduate Masters Theses. 525.